Papers

Full list of publications: Google Scholar.

1. 2025 Spatiotemporally resolved GPCR interactome uncovers unique mediators of receptor agonism
   MM Shchepinova^✉, R Richardson, JW Houghton, AR Walker, MA Safar, D Conole, AC Hanyaloglu, EW Tate.
   Cell Chemical Biology, 2025, 32 (5), 722–735
2. 2024 Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling
   Y Manchanda, L ElEid, AI Oqua, Z Ramchunder, J Choi, MM Shchepinova, ... B Jones, A Tomas.
   Science Signaling, 2024, 17 (843)
3. 2023 Discovery of lipid-mediated protein–protein interactions in living cells using metabolic labeling with photoactivatable clickable probes
   RO Fedoryshchak, A Gorelik, M Shen, MM Shchepinova, I Pérez-Dorado, EW Tate.
   Chemical Science, 2023, 14(9), 2419–2430
4. 2020 Antibody–PROTAC conjugates enable HER2-dependent targeted protein degradation of BRD4
   MA Maneiro, N Forte, MM Shchepinova, CS Kounde, V Chudasama, JR Baker, EW Tate.
   ACS Chemical Biology, 2020, 15(6), 1306–1312
5. 2020 A caged E3 ligase ligand for PROTAC-mediated protein degradation with light
   CS Kounde, MM Shchepinova, CN Saunders, M Muelbaier, MD Rackham, JD Harling, EW Tate.
   Chemical Communications, 2020, 56(41), 5532–5535
6. 2020 Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells
   Z Fang, S Chen, Y Manchanda, S Bitsi, P Pickford, A David, MM Shchepinova, ... A Tomas, B Jones.
   International Journal of Molecular Sciences, 2020, 21(21), 8404
7. 2020 Internalization-dependent free fatty acid receptor 2 signaling is essential for propionate-induced anorectic gut hormone release
   N Caengprasath, N Gonzalez-Abuin, M Shchepinova, Y Ma, A Inoue, EW Tate, G Frost, AC Hanyaloglu.
   iScience, 2020, 23 (9), 101449
8. 2020 Chemical biology of noncanonical G protein–coupled receptor signaling: Toward advanced therapeutics
   MM Shchepinova^✉, AC Hanyaloglu, GS Frost, EW Tate.
   Current Opinion in Chemical Biology, 2020, 56, 98–110
9. 2017 MitoNeoD: a mitochondria-targeted superoxide probe
   MM Shchepinova, AG Cairns, TA Prime, A Logan, AM James, AR Hall, ... MP Murphy, RC Hartley.
   Cell Chemical Biology, 2017, 24 (10), 1285–1298
10. 2016 A cell-permeable biscyclooctyne as a novel probe for the identification of protein sulfenic acids
    DJ McGarry, MM Shchepinova, S Lilla, RC Hartley, MF Olson.
    ACS Chemical Biology, 2016, 11(12), 3300–3304
11. 2015 Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat
    EL Robb, JM Gawel, D Aksentijević, HM Cochemé, TS Stewart, MM Shchepinova, ... RC Hartley, MP Murphy.
    Free Radical Biology and Medicine, 2015, 89, 883–894
12. 2014 Dodecyl and octyl esters of fluorescein as protonophores and uncouplers of oxidative phosphorylation in mitochondria at submicromolar concentrations
    MM Shchepinova, SS Denisov, EA Kotova, LS Khailova, DA Knorre, ... FF Severin, YN Antonenko.
    Biochimica et Biophysica Acta (BBA) – Bioenergetics, 2014, 1837(1), 149–158